This project aims to integrate mobility, land use and infrastructure into a resilient, adaptive system that responds to changing needs, through a three-pronged approach. Social network surveys will monitor and examine the activity chains that generate demand for mobility. Second, novel modelling techniques will be developed to handle the unique challenges posed by the fast-changing and dynamic nature of cities through adaptive systems, that can respond to disruptions almost in real-time. Finally, exploratory modelling, decision-making under uncertainty methods (e.g. real-options) and optimization methods will be employed to formulate adaptive plans that can response respond to long-term changes. Our research endeavours span the global scope, with a particular emphasis on contributing to the development of Singapore and Zurich. Our ultimate objective is to develop adaptive plans that can effectively navigate uncertainties and lead to long-term desirable outcomes aligned with carbon neutrality and/or the 45-Minute City targets by 2050.